Allergy means ‘change in activity’. It also known as hypersensitive reaction and happens when body defense system reacts to foreign substance that enters the body through the skin, lung, swallowed or pricked skin. This reaction does not need to happen everyone. It happened more often to those who have family’s history who suffered allergy. Common allergic reactions include eczema, hives, hay fever, asthma attacks, food allergies, and reactions to the venom of stinging insects such as wasps and bees.
Allergic reaction could be mild, or serious and it can happen in a blink of an eye or few minutes after being exposed to allergen, but some possibly could happen after several days or few weeks. Anaphylaxis is a very serious allergic reaction and can happen rapidly within a few minutes after being exposed to the allergen. It brings to anaphylactic shock and can cause death within 15 minute if the victim does not get medical treatment.
The term ‘allergy’ was created by a Vienna pediatrician, Clemens von Pirquet in 1906 after he made his note that some of his patients are hypersensitive to normally harmless entities such as dust, pollen, or some particular food. Pirquet names this phenomenon as ‘allergy’, from Greek words allos which means “other” and ergon mean “reaction”.
Historically, all forms of hypersensitivity are classified as allergies, and all were thought to be caused by an improper activation the body immune system. Later, it became clear that several different disease mechanisms were implicated, with the common link to a disordered activation of the immune system.
In 1963, a new classification scheme was designed by Philip Gell and Robin Coombs that described four types of hypersensitivity reactions, known as Type I to Type IV hypersensitivity. With this new classification, the word “allergy” was restricted to type I hypersensitivities (also called immediate hypersensitivity), which are characterized as rapidly developing reactions.
A major breakthrough in understanding the mechanisms of allergy was the discovery of the antibody class labeled immunoglobulin E (IgE) – Kimishige Ishizaka and co-workers were the first to isolate and describe IgE in the 1960s.
What Are The Common Causes of Allergic Reaction?
Here are the common causes of allergic reaction:
- Bee sting
- Insect or animal bite
Things that causes allergic reaction are also known as allergen.